RGNCY-0015 (CPD5 - MPS-TTK Inhibitor)

IN STOCK!!  E-mail us at info@reagency.co if you are interested in this product.

RGNCY-0015 is a protein kinase inhibitor with activity against MPS1/TTK. It has an IC50 of 0.10 µM in cellular proliferation inhibition assay using A2780 cells.

Systematic Name: N-(2,6-diethylphenyl)-8-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide


Molecular Weight:

Formula: C33H40N8O2

PMID: 21723120

Reference: Caldarelli, Marina, et al. "Synthesis and SAR of new pyrazolo [4,3-] quinazoline-3-carboxamide derivatives as potent and selective MPS1 kinase inhibitors." Bioorganic & Medicinal Chemistry Letters 21.15 (2011): 4507-4511.

Data Sheet


Interested in this reagent? E-mail us at info@reagency.co and let us know.

Tags: TTK, RGNCY-0015, CPD5, MPS, A2780